transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding

signal transducer, downstream of receptor, with serine/threonine kinase activity

intracellular cyclic nucleotide activated cation channel activity

RNA polymerase I regulatory region sequence-specific DNA binding

transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity

RNA polymerase I upstream control element sequence-specific DNA binding

glutamine-fructose-6-phosphate transaminase (isomerizing) activity

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

signal transducer, downstream of receptor, with protein tyrosine phosphatase activity

oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor

voltage-gated sodium channel activity involved in Purkinje myocyte action potential

ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol

transferase activity, transferring acyl groups other than amino-acyl groups

voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

ATPase activity, coupled to transmembrane movement of substances

mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity

dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity

cyclin-dependent protein serine/threonine kinase regulator activity

4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor

oxidoreductase activity, acting on the aldehyde or oxo group of donors

inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity

dolichyl-diphosphooligosaccharide-protein glycotransferase activity

transcription factor activity, sequence-specific DNA binding transcription factor recruiting

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity

transferase activity, transferring alkyl or aryl (other than methyl) groups

inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

ubiquitin-specific protease activity involved in positive regulation of ERAD pathway

beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

ion antiporter activity involved in regulation of postsynaptic membrane potential

G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential

oxidoreductase activity, oxidizing metal ions, oxygen as acceptor

intramolecular oxidoreductase activity, interconverting keto- and enol-groups

inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

gap junction channel activity involved in cardiac conduction electrical coupling

sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding

cysteine-type endopeptidase activity involved in execution phase of apoptosis

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

secondary active monocarboxylate transmembrane transporter activity

exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

cysteine-type endopeptidase activity involved in apoptotic process

oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor

single-stranded DNA-dependent ATP-dependent DNA helicase activity

gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling

gap junction channel activity involved in cell communication by electrical coupling

oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor

transcriptional repressor activity, RNA polymerase II transcription factor binding

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

cysteine-type endopeptidase activity involved in apoptotic signaling pathway

tricarboxylate secondary active transmembrane transporter activity

transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism

voltage-gated potassium channel activity involved in SA node cell action potential depolarization

N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization

N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

phosphoribosylaminoimidazolesuccinocarboxamide synthase activity

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

transcription factor activity, RNA polymerase II core promoter sequence-specific

oxidoreductase activity, acting on other nitrogenous compounds as donors

8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity

RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding

electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity

secondary active oligopeptide transmembrane transporter activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

voltage-gated calcium channel activity involved in AV node cell action potential

steroid dehydrogenase activity, acting on the CH-CH group of donors

RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding

cysteine-type endopeptidase activator activity involved in apoptotic process

RNA polymerase II sequence-specific DNA binding transcription factor binding

carbon-nitrogen ligase activity, with glutamine as amido-N-donor

transforming growth factor beta receptor, common-partner cytoplasmic mediator activity

ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

phosphotransferase activity, for other substituted phosphate groups

oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor

RNA polymerase II transcription factor activity, sequence-specific DNA binding

site-specific endodeoxyribonuclease activity, specific for altered base

proton-dependent oligopeptide secondary active transmembrane transporter activity

all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated

oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor

transcriptional activator activity, RNA polymerase II transcription factor binding

calcium-dependent cysteine-type endopeptidase inhibitor activity

glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity

low-affinity basic amino acid transmembrane transporter activity

calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential

oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor

oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor

oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor

high-affinity basic amino acid transmembrane transporter activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding

voltage-gated calcium channel activity involved in bundle of His cell action potential

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity

oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor

transmembrane receptor protein tyrosine kinase activator activity

racemase and epimerase activity, acting on carbohydrates and derivatives

oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters

3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity

gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling

oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor

17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

voltage-gated calcium channel activity involved in cardiac muscle cell action potential

phosphatidyl-N-dimethylethanolamine N-methyltransferase activity

voltage-gated potassium channel activity involved in SA node cell action potential repolarization

nucleobase-containing compound transmembrane transporter activity

galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity

voltage-gated sodium channel activity involved in AV node cell action potential

adenylate cyclase inhibiting G-protein coupled glutamate receptor activity

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor

dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity

RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding

racemase and epimerase activity, acting on amino acids and derivatives

enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity

calcium ion binding involved in regulation of cytosolic calcium ion concentration

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

intronic transcription regulatory region sequence-specific DNA binding

voltage-gated sodium channel activity involved in cardiac muscle cell action potential

transcription factor activity, direct ligand regulated sequence-specific DNA binding

inositol bisdiphosphate tetrakisphosphate diphosphatase activity

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

voltage-gated calcium channel activity involved SA node cell action potential

cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

transcription factor activity, RNA polymerase II transcription factor binding

oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor

sodium-dependent organic anion transmembrane transporter activity

UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity

oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor

neutral L-amino acid secondary active transmembrane transporter activity

sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity

RNA polymerase III transcription factor activity, sequence-specific DNA binding

inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity

transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity

transcription factor activity, RNA polymerase I transcription factor binding

extracellular matrix structural constituent conferring compression resistance

hydrolase activity, acting on acid halide bonds, in C-halide compounds

transforming growth factor beta receptor, cytoplasmic mediator activity

ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity

protein binding, bridging involved in substrate recognition for ubiquitination

alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

5,10-methylenetetrahydrofolate-dependent methyltransferase activity

oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

RNA polymerase II regulatory region sequence-specific DNA binding

oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor

8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity

[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity

transcription factor activity, ligand-activated RNA polymerase II transcription factor binding

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines

N-acylphosphatidylethanolamine-specific phospholipase D activity

oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor

Intermediate conductance calcium-activated potassium channel activity

RNA polymerase I transcription factor activity, sequence-specific DNA binding

sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

pituitary adenylate cyclase-activating polypeptide receptor activity

transcription factor activity, RNA polymerase III transcription factor binding

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity

template for synthesis of G-rich strand of telomere DNA activity

neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential

hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances

oxidoreductase activity, acting on phosphorus or arsenic in donors

oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor

oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor

oxidoreductase activity, acting on diphenols and related substances as donors

RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending

oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor

transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting

oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding

sodium-independent organic anion transmembrane transporter activity

electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity

transcription factor activity, RNA polymerase II basal transcription factor binding

transcription factor activity, RNA polymerase I transcription factor recruiting

secondary active organic cation transmembrane transporter activity

oxidoreductase activity, acting on superoxide radicals as acceptor

alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity

calmodulin-dependent cyclic-nucleotide phosphodiesterase activity

transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding

3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity

oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor

transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly

lysine N-acetyltransferase activity, acting on acetyl phosphate as donor

voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization

UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity

oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor

oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor

neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

pituitary adenylate cyclase-activating polypeptide receptor binding

tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

signal transducer, downstream of receptor, with protein tyrosine kinase activity

transcriptional repressor activity, RNA polymerase II activating transcription factor binding

transcription factor activity, RNA polymerase I CORE element sequence-specific binding

oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor

3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity

transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting

cyclin-dependent protein serine/threonine kinase activator activity

magnesium-dependent protein serine/threonine phosphatase activity

voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential

cyclin-dependent protein serine/threonine kinase inhibitor activity

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

protein-L-isoaspartate (D-aspartate) O-methyltransferase activity

sodium-dependent multivitamin transmembrane transporter activity

2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity

RNA polymerase II transcription factor activity, TBP-class protein binding

gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling

voltage-gated sodium channel activity involved in bundle of His cell action potential

phosphoribosylaminoimidazolecarboxamide formyltransferase activity

hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity

transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding

granulocyte macrophage colony-stimulating factor receptor binding

RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding

calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration

protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity

P-P-bond-hydrolysis-driven protein transmembrane transporter activity

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen

signal transducer, downstream of receptor, with serine/threonine phosphatase activity

oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor

N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity

RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

cysteine-type endopeptidase regulator activity involved in apoptotic process

RNA polymerase II core promoter proximal region sequence-specific DNA binding

enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity

ubiquitin-specific protease activity involved in negative regulation of ERAD pathway

dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity

N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity

voltage-gated sodium channel activity involved in SA node cell action potential

ligand-dependent nuclear receptor transcription coactivator activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

intramolecular oxidoreductase activity, interconverting aldoses and ketoses

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity

oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor

beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity

CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity

transcription factor activity, RNA polymerase II transcription factor recruiting

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity